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Why doesn’t your treatment contain Tretinoin or Isotretinoin (Accutane®)?

Why doesn’t your treatment contain Tretinoin or Isotretinoin (Accutane®)?123

We made an active decision not to use either Tretinoin or Isotretinoin (Accutane®) as after research neither was an effective or attractive treatment for Fordyce Condition.

Tretinoin is used in some high-dose acne treatments and is an acid form of vitamin A, it has some unfortunate side effects such as creating red sores on the skin.

Isotretinoin or ‘Accutane’ is a medication and is often used in chemotherapy. It is also used for very severe acne, however when treatment stops, symptoms return. There have been few reported successes with ‘Accutane’ for Fordyce Spot treatment, and we felt it unwise to use such a strong treatment which causes a number of side effects:

Dryness of skin, lips and mucous membranes, skin fragility, skin peeling, rash, flushing, nose bleeds, dry eyes, eye irritation, conjunctivitis, reduced tolerance to contact lenses, hyperlipidaemia, raised liver enzymes, permanent thin skin, headaches, permanent hair thinning (This could start or continue after treatment), cataracts and erectile dysfunction.

As an alternative we have opted to use Vitamin E Acetate, a vitamin E supplement to reduce the toxicity of this high-dose retinoid without reducing its active properties.


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